Estella Gustilo’s expertise is in the life sciences. She has a B.S. in Biology and a Ph.D. in Biochemistry.
Her work in science began at the Medical University of SC (MUSC), studying diabetes 1 with the use of rat models. She then worked at MeadWestvaco Forest Science Lab in SC, where she helped genetically engineer trees that were more efficient in paper production. Back at MUSC, Estella studied the molecular signaling pathway of pulmonary fibrosis and learned how certain biomolecules can affect the malfunctioning of apoptosis which is the main characteristic of fibrotic cells.
In graduate school at North Carolina State University (NCSU), Estella worked to understand how modifications affect RNA structure and function. She learned how modifications at the anticodon of tRNA can influence the rate of protein synthesis. She received a National Science Foundation Fellowship and a NCSU Scholarship for her graduate work.
After graduate school, Estella worked at the Scripps Research Institute in La Jolla, CA studying protein folding. She helped develop high-throughput assays used to test small molecules and their effect on protein folding, specifically the misfolding of protein Transthyretin, which causes debilitating disease and often results in death. After working at Scripps, Estella then went on to study the translation initiation of mRNA, specifically of the plant viral RNA BYDV and the human tumor suppressor p53 mRNA.
Estella’s research led to her to co-author multiple, highly-cited, peer-reviewed articles in renowned scientific journals.
After years of biochemistry and molecular biology research, Estella then went on to teach at several universities in New York City (CUNY, NYIT) and briefly at George Mason University. She has taught a variety of Chemistry courses, such as General Chemistry, Organic Chemistry, Biochemistry, Biophysical Chemistry, and others. She has also taught a few courses of Biology.
She now specializes in prosecution of chemical and life-science patent applications.